Feel as Good as You Look.

Dr. Gail Humble has led the rejuvenation movement from the cutting edge of cosmetic medicine and regenerative science. She is a trailblazing geneticist leading the world in understanding and applying aesthetic medicine.

Dr. Humble will guide your vitality journey with cellular rejuvenation grounded in 28 years of genetic research. From age-suppressing Klotho treatments and volumizing regeneration injections through cellular optimization, her practice features best-in-class regenerative aesthetics that work with your body’s natural biology for long-lasting and natural-looking results.

Our vision statement was always “you should look as good as you feel”. Studying the Klotho gene and cellular optimization changed everything. As we get older we want to “Feel as good as we look”

Speaking at the World's Leading Conferences

Driving Aesthetics Innovation

Dr. Humble has built one of the most respected non-surgical cosmetic practices in parallel with an inspiring intellectual research career. Both sides complement each other as she sees patients enjoying the natural results of techniques developed from her research.

By the Numbers

Integrating Applied Research

As a leading geneticist in the field, Dr. Humble is often asked to speak internationally and consult with industry leaders such as Allergan, Steifel, Galderma, Dermik, Sanofi-Aventis, Valeant, Lumenis, and KMI.

She has served as an associate professor at USC and affiliate staff @UCSF. Her research appears in Dermatologic Surgery, the Journal of Plastic and Reconstructive Surgery, Skin and Aging, the European Journal of Medicine, and Dermatologic Drugs, among others.

Spearheading the Science of Sculptra

Dr. Humble is one of the first cosmetic physicians in the world to work with Sculptra. As co-investigator of the FDA clinical trials that defined the treatment standard, she built Sculptra’s scientific foundation through years of dedicated research and over 40 published studies. This injectable stimulates collagen, prompting the body to stimulate collagen production for long-lasting and natural rejuvenation.

Advocating for Anti-Aging with Klotho

Dr. Humble is one of the first cosmetic physicians in the world to work with Sculptra. As co-investigator of the FDA clinical trials that defined the treatment standard, she built Sculptra’s scientific foundation through years of dedicated research and over 40 published studies. This injectable stimulates collagen, prompting the body to stimulate collagen production for long-lasting and natural rejuvenation.
Dr. Gail Humble

Expertise

  • B.S. Genetics, UC Davis
  • M.D., University of Texas Medical Branch, Galveston
  • Residency in Anesthesiology, University of Southern California
  • Associate Professor, USC
  • FDA Sculptra Co-Investigator (one of two physicians in the United States)
  • Klotho Patent Holder (two patents)
  • XPRIZE Top-100 Finalist
  • Board certification in Anesthesia
  • Fellow of the Aesthetic Anti-Aging Congress and General Surgery Internship
  • Medical Director of the Aesthetic Anti-Aging Institute

Experience

  • Allergan · Galderma · Dermik · Sanofi-Aventis · Lumenis
  • Society of Regenerative Medicine
  • International Society for Stem Cell Research (ISSCR)
  • American Academy of Anti-Aging Medicine (A4M)
  • AMWC World Congress

Integrating Longevity Science with Aesthetic Excellence

Dr. Humble’s practice embodies the industry's best standard practices for aesthetic rejuvenation. Each treatment she offers represents the peak product of scientific expertise, honed over multiple decades of research and clinical practice.

Each treatment begins with an educational consultation, helping you understand the emerging landscape of regenerative biology, because Dr. Humble's approach is personalized to your biology. Dr. Humble will work with you to discover the individualized approach that aligns with your health goals.

Bringing Klotho to Clinical Practice

The Klotho gene is the only documented aging suppressor gene in mammals. When overexpressed, it extends a healthy lifespan. When disrupted, it accelerates aging. Dr. Gail Humble is a world expert in Klotho genetics and application. Dr. Humble served as PI in the cellular research studies, published 3 cellular studies and 3 peer-reviewed studies on it, and led three IRB-approved clinical trials. She hold patents on the process of genetically modifying human mesenchymal stem cells to upregulate Klotho expression, enabling reliable production of Klotho protein for clinical use. That science is the foundation of her treatments, her Klotho Skin line, and her approach to longevity medicine. You can even test your own Klotho levels to take a first step toward understanding where you are biologically and where you could be.

Why Klotho Matters

  • Cellular Longevity. Klotho protects cells from oxidative stress and extends their healthy lifespan. Klotho protects cells from oxidative stress and extends their healthy lifespan.
  • Collagen Support. Klotho stimulates collagen III production and reduces transepidermal water loss, producing firmer, more resilient skin from within the cellular architecture.
  • Whole-Body Vitality. Beyond skin, Klotho influences cognitive function, cardiovascular health, and systemic inflammation. It governs aging throughout the body.
  • Know Your Levels. Dr. Humble offers Klotho testing, a clinical first step toward measuring and optimizing your personal longevity biology.

Ready To Learn How To Work With Your Biology?

Begin with a consultation. Dr. Humble takes time to understand your goals, both aesthetic and systemic, and designs a personalized protocol that works with your biology. Whether you are exploring facial rejuvenation, Klotho science, or cellular optimization, this is where to start.
Serving patients in San Francisco, the Bay Area, and Simi Valley.

Locations

Serving patients in San Francisco, the Bay Area, and Simi Valley. International patients are welcome. Dr. Humble lectures and consults globally.